1. Combine Worcestershire sauce, garlic powder, onion powder, smoked paprika, and black pepper in small bowl. Mix well and set aside while you prep the beef.

2. Place ground beef in large bowl and pour seasoning mixture over top. Use hands to mix gently until seasonings distribute evenly. Avoid overworking the meat or burgers get tough.

3. Divide mixture into 6-8 equal portions depending on desired burger size. Gently form each portion into a patty slightly larger than your buns.

4. Press your thumb into center of each patty to create a small indentation. This prevents burgers from puffing up into balls during cooking and helps them stay flat.

5. Sprinkle both sides of patties with salt right before cooking. Grill over medium-high heat for 4-5 minutes per side for medium doneness. Adjust time based on thickness and preferred doneness.

6. Let burgers rest for 5 minutes after cooking. This allows juices to redistribute throughout the meat for maximum juiciness in every bite.